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genetic

Genetic and Familial Factors of specific phobias

Genetic and Familial Factors First-degree relatives of people with specific phobias are more likely themselves to have a specific phobia providing evidence for the importance of either genetic or environmental family factors in the disorder. More specifically, a few twin studies demonstrated a genetic involvement in specific phobias but the importance of environmental factors was […]

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genetic factors social phobia

genetic factors social phobia As for the other anxiety disorders, family studies showed a higher concordance for social phobia among the f irst-degree relatives of people with the disorder. In contrast, twin studies typically demonstrated that most of the genetic variance is consistent with the importance of a general neurotic syndrome. However, there has also […]

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panic disorder genetic factors

panic disorder Genetic and Familial Factors A series of early studies conducted by a group of researchers in Iowa indicated that panic disorder subjects were more likely to have first-degree relatives with panic disorder (or agoraphobia) than nonanxious controls or subjects with other anxiety disorders. Such data have often been cited as evidence for a […]

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Schizophrenia Genetic Studies

The massive literature on the genetics of schizophrenia can be assimilated into a multifactorial polygenic model but cannot be made to fit a singlemajor-locus model with high penetrance. There is no clear evidence against a simple multifactorial polygenic model, but Gottesman notes the possibility of a mixed model. This model includes a small number of […]

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Molecular Genetic Studies of Psychopathology

Molecular Genetic Studies of Psychopathology Molecular genetic studies of most major forms of psychopathology have become a major area of contemporary etiological research. Approaches to f inding genes that underlie psychiatric disorders have included both association studies of the role of specific candidate genes, as well as genome scans of anonymous DNA markers by using […]

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genetic and environmental influences on depression and anxiety

Inclusion of Specific Environmental and Endophenotypic Variables in Behavior Genetic Models Standard behavior genetic analyses represent genetic and environmental influences as unspecif ied, anonymous, or ‘‘black box’’ variables. Kendler notes that the statistical power to detect shared environmental influences is low in such standard models, whereas incorporating specified environmental variables within a behavior genetic model […]

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Is Schizophrenia Genetic or Environmental

Is Schizophrenia Genetic or Environmental?Many family studies have been conducted to establish that a familial association exists between these disorders and schizophrenia, but fewer twin and adoption studies have been conducted to investigate the role that genetic influences play in their etiology. As stated earlier, different models exist to explain the genetic transmission of the […]

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Multivariate Behavior Genetic Studies of Mood and Anxiety

Disorder Symptoms Most multivariate behavior genetic contributions to the classification of mood and anxiety disorders have been based on three general approaches: (1) split an existing diagnostic category into subtypes and examine differences in the causes of the resulting subtypes; (2) look for common causes that cut across the symptoms of several diagnostic categories, using […]

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Genetic factors of anorexia and bulimia

Genetic factors Genetic factors may contribute to risk for both anorexia and bulimia. Klump et al., for example, estimated 74 per cent of the variance in anorexic behaviours to be attributable to genetic factors, following a twin study in which they found 50 per cent of MZ twins and no DZ twins to be concordant […]

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