Mental health articles

OF mental health care and mentally ill

mechanism

a mechanism underlying substance abuse

Substance Abuse Major aspects of the literature on substance abuse fit particularly well with the motivational model. Although at one time it was argued that drug abuse could be attributed to physiological dependence per se, there has been a substantial move toward the view that ‘‘abuse of reinforcers’’ conveys the essence of drug abuse, either […]

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Typical antipsychotics mechanism of action

Typical antipsychotics Mechanism of action  Extensive research was undertaken into the mechanisms of action of typical antipsychotics. This has led to the development of a range of theories regarding the pathology of psychosis. Over time, it became clear that it was the ability to act as a dopamine antagonist that produced the clinically desirable effect, […]

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Atypical antipsychotics mechanism of action

Atypical antipsychotics The term ‘atypical’ is applied to the second generation of antipsychotics owing to their reduced propensity to cause EPSEs. The fi rst of this group was clozapine, which was fi rst synthesised in 1958. After initial launch in the 1970s it was withdrawn because of the recognition of previously unidentifi ed and potentially […]

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