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list of multifactorial disorders
list of multifactorial disorders Disease with multiple etiology Multifactorial disease such as work-related diseases,
for example hypertension, coronary heart disease,
chronic non-specific respiratory disease, low back syndrome,
upper limb disorders, cancer, etc., are thought
to be caused by complex interactions between genetic
factors (polygenic basis) and various environmental
factors. The term multifactorial means that there are
many different influences acting together to cause the
appearance of the disease. These include effects from
a combination of genetic factors, none of which on its
own would be likely to cause the disease, and environmental
factors, which again would not cause the disease
by themselves. It is believed that a particular combination
of genetic and environmental factors act together
in concert and trigger the development of multifactorial
disease.
Different environmental factors will influence the development of different multifactorial diseases. Besides environmental and workplace factors (chemical, physical, ergonomic, or psychosocial stressors), non-occupational life-style factors (diet, weight, type and amount of exercise, and smoking and drinking) also place genetically susceptible individuals at risk of developing multifactorial diseases.
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